Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706071 | 0.89 | LMNA (0.42) | MAPTHSD17B10LMNARAB9AKDM4E | |
| SCHEMBL8027446 | 0.77 | KDM4E (0.61) | MAPTHSD17B10LMNARAB9AKDM4E | |
| SCHEMBL9706134 | 0.76 | ALDH1A1 (0.38) | MAPTHSD17B10LMNARAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL8025752 | 0.76 | KDM4E (0.59) | MAPTHSD17B10LMNARAB9AKDM4E | |
| SCHEMBL9706283 | 0.75 | MAPT (0.49) | MAPTHSD17B10LMNAHPGDPOLB | |
| SCHEMBL9706132 | 0.72 | MAPT (0.51) | MAPTHSD17B10KDM4EALDH1A1TP53 | |
| Dimethylamine SCHEMBL9706291 | 0.72 | RPS6KA5 (0.49) | MAPTHSD17B10LMNARAB9AKDM4E | |
| SCHEMBL6930941 | 0.68 | CYP1A2 (0.51) | MAPTHSD17B10LMNARAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL6934110 | 0.67 | CYP1A2 (0.50) | MAPTHSD17B10LMNARAB9AKDM4E | |
| SCHEMBL9706152 | 0.67 | MEN1 (0.45) | MAPTLMNARAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238459-B1 | SUBSTITUTED INDOLOQUINOXALINES | Lundblad, Leif (SE) | 1992-04-15 | — | — | EP | disclosed |
| US-4990510-A | Viricides, anticancer agents | LEIF LUNDBLAD (BE) | 1991-02-05 | — | — | US | disclosed |
| EP-0238459-A1 | Substituted indoloquinoxalines | Lundblad, Leif (SE) | 1987-09-23 | — | — | EP | disclosed |
| WO-1987004436-A1 | SUBSTITUTED INDOLOQUINOXALINES | LUNDBLAD, LEIF (SE) | 1987-07-30 | — | — | WO | disclosed |