SCHEMBL9706294

SCHEMBL9706294

CCCC(O)C1C(CO)CC1n1ccc(=O)[nH]c1=O

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.39
SLC28A2 O43868 1/20 0.39
SLC29A1 Q99808 1/20 0.39
SLC28A3 Q9HAS3 1/20 0.39
P2RY2 P41231 3/20 0.34
P2RY4 P51582 1/20 0.34
PKM P14618 1/20 0.33
DUT P33316 2/20 0.32
CRBN Q96SW2 1/20 0.31
TK1 P04183 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9706098 0.91 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL9706103 0.87 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL9706112 0.81 TK1 (0.47) TK1
SCHEMBL9706120 0.80 LMNA (0.45) TK1
SCHEMBL9310399 0.78 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL9706072 0.77 LMNA (0.42) SLC29A1
SCHEMBL9471434 0.76 SLC28A1 (0.47) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL10465785 0.76 SLC28A1 (0.53) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL10338226 0.76 SLC28A1 (0.53) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL9470704 0.76 SLC28A1 (0.47) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0481320-A1 Novel cyclobutane derivatives NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1992-04-22 EP disclosed