Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TK2 | O00142 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706133 | 0.91 | TK1 (0.48) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL9706120 | 0.88 | LMNA (0.45) | TK1LMNATK2 | |
| SCHEMBL9706089 | 0.87 | TK1 (0.51) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL9706162 | 0.83 | TK1 (0.56) | TK1BLMTK2 | |
| SCHEMBL9706294 | 0.81 | SLC28A1 (0.39) | TK1 | |
| SCHEMBL9310153 | 0.80 | TK1 (0.60) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL9706167 | 0.78 | LMNA (0.49) | TK1LMNAADRA1ATK2 | |
| SCHEMBL8689341 | 0.78 | TK1 (0.54) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL10516729 | 0.78 | TK1 (0.57) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL10514914 | 0.78 | TK1 (0.57) | TK1ALDH1A1LMNAALBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481320-A1 | Novel cyclobutane derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-04-22 | — | — | EP | disclosed |