SCHEMBL970633

SCHEMBL970633

CCCCCCCCCCCCCCCCCC[Si](C)(C)O

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
THRB P10828 1/20 0.47
LMNA P02545 2/20 0.43
ALDH1A1 P00352 2/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
EPHX1 P07099 4/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
CES2 O00748 3/20 0.38
CES1 P23141 3/20 0.38
DNM1 Q05193 4/20 0.36
SLC22A1 O15245 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17090808 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL1494411 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL17090767 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL17090817 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL17090830 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL17090825 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL17090810 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL1494418 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL1494194 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL7102962 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118027672-A 3D (three-dimensional) direct writing printing porous silicon rubber and preparation method thereof 中国科学院化学研究所 2024-05-14 CN disclosed
CN-117986876-A Organic silicon foam and preparation method thereof 中国科学院化学研究所 2024-05-07 CN disclosed
CN-114262341-B Method for preparing silanol by photocatalytic oxidation of silane 西安交通大学 2023-05-02 CN disclosed
CN-114262341-A Method for preparing silanol by utilizing photocatalytic oxidation of silane 西安交通大学 2022-04-01 CN disclosed
CN-109415447-B Silane-mediated enhancement of rubber storage stability 盛禧奥欧洲有限责任公司 2021-06-15 CN disclosed
CN-106146851-B Photocurable composition and cured product containing same 信越化学工业株式会社 2020-10-23 CN disclosed
US-10787562-B2 Silane-mediated enhancement of rubber storage stability TRINSEO EUROPE GMBH (CH) 2020-09-29 US disclosed
US-10730904-B2 Method for liquid-phase synthesis of nucleic acid TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2020-08-04 US disclosed
EP-2921499-B1 METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACIDS TAKEDA PHARMACEUTICALS CO (JP) 2020-01-22 EP disclosed
EP-3093303-B1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT SHINETSU CHEMICAL CO (JP) 2019-08-28 EP disclosed
EP-0452725-A2 Fluorine containing diaminobenzene derivatives and its use SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-23 EP disclosed
EP-0278368-B1 A METHOD FOR PRODUCING CHLOROSILANES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-09-19 EP disclosed
EP-0377175-A2 Pattern forming composition and process for forming pattern using the same HITACHI, LTD. (JP) 1990-07-11 EP disclosed
EP-0344891-A2 Tetraazaporphin, process for producing the same, as well as optical recording media using the same and production processes thereof Hitachi Chemical Co., Ltd. (JP) 1989-12-06 EP disclosed
US-4780556-A Method for producing chlorosilanes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-10-25 US disclosed
EP-0278368-A1 A method for producing chlorosilanes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-08-17 EP disclosed
EP-0101597-B1 PROCESS FOR THE PREPARATION OF ASTAXANTHINE AND INTERMEDIATES IN THE ASTAXANTHINE SYNTHESIS F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1988-06-22 EP disclosed
US-4585885-A INTERMEDIATES FOR ASTAXANTHIN HOFFMANN-LA ROCHE INC. (US) 1986-04-29 US disclosed
EP-0101597-A2 Process for the preparation of astaxanthine and intermediates in the astaxanthine synthesis F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1984-02-29 EP disclosed
US-3972982-A EXTRACTION WITH A SILANE AND A HYDROCARBYL AMINE MONSANTO COMPANY (US) 1976-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10730904-B2 Method for liquid-phase synthesis of nucleic acid RNGTT, POLR2H, POLR2E TSHR 411/4885THRB 1249/4885LMNA 204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.