Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090808 | 1.00 | TSHR (0.47) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| SCHEMBL1494411 | 1.00 | TSHR (0.47) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| SCHEMBL17090767 | 1.00 | TSHR (0.47) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| SCHEMBL17090817 | 1.00 | TSHR (0.47) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| SCHEMBL17090830 | 1.00 | TSHR (0.47) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| SCHEMBL17090825 | 1.00 | TSHR (0.47) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| SCHEMBL970633 | 1.00 | TSHR (0.47) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| SCHEMBL17090810 | 1.00 | TSHR (0.47) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| SCHEMBL1494418 | 1.00 | TSHR (0.47) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| SCHEMBL1494194 | 1.00 | TSHR (0.47) | TSHRTHRBLMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730904-B2 | Method for liquid-phase synthesis of nucleic acid | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-08-04 | — | — | US | disclosed |
| EP-2921499-B1 | METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACIDS | TAKEDA PHARMACEUTICALS CO (JP) | 2020-01-22 | — | — | EP | disclosed |
| US-20190135852-A1 | METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACID | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-05-09 | — | — | US | disclosed |
| US-20150315229-A1 | METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACID | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-11-05 | — | — | US | disclosed |
| EP-2921499-A1 | METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACID | Takeda Pharmaceutical Company Limited (JP) | 2015-09-23 | — | — | EP | disclosed |
| EP-0838721-B1 | Processing method of silver halide light sensitive photo graphic material | KONISHIROKU PHOTO IND (JP) | 2003-09-10 | — | — | EP | disclosed |
| EP-0903350-B1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-5962209-A | TABULAR SILVER HALIDE GRAINS HAVING AN ASPECT RATIO OF 2 TO 15, (100) MAJOR FACES WITH AN EDGE RATIO OF 1 TO 2, AND A SILVER CHLORIDE CONTENT OF 50 MOL % OR MORE; AND SAID EMULSION LAYER FURTHER CONTAINING A LEUCO COMPOUND CAPABLE OF FORMING A | KONICA CORPORATION (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0518238-B1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| EP-0903350-A1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1999-03-24 | — | — | EP | disclosed |
| EP-0838721-A1 | Processing method of silver halide light sensitive photo graphic material | KONICA CORPORATION (JP) | 1998-04-29 | — | — | EP | disclosed |
| EP-0484857-B1 | Polyorganosiloxane having a quaternary salt at its one terminal and percutaneous absorption-promoting agent | SAGAMI CHEM RES (JP) | 1997-05-07 | — | — | EP | disclosed |
| US-5508421-A | Pyrrolotriazole azomethine dye, and heat transfer dye providing material containing a pyrrolotriazole azomethine dye | FUJI PHOTO FILM CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| US-5391720-A | Imidazole azo dyes with sharp absorption wave, colorfastness | FUJI PHOTO FILM CO., LTD. (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5362882-A | Intermediates for dyes for polyesters, images for heat sensitive elements and electrography | FUJI PHOTO FILM CO., LTD. (JP) | 1994-11-08 | — | — | US | disclosed |
| US-5344933-A | Pyrrole ring-or condensed pyrrole ring-containing azomethine dye | FUJI PHOTO FILM CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |
| EP-0545420-A2 | Imidazole azo dyes and thermal transfer dye donating materials containing them | FUJI PHOTO FILM CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |
| US-5200488-A | POLYORGANOSILOXANE HAVING A QUATERNARY SALT AT ITS ONE TERMINAL AND PERCUTANEOUS ABSORPTION-PROMOTING AGENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1993-04-06 | — | — | US | disclosed |
| EP-0518238-A1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |
| EP-0484857-A2 | Polyorganosiloxane having a quaternary salt at its one terminal and percutaneous absorption-promoting agent | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150315229-A1 | METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACID | POLM, POLRMT, RNMT | TSHR 495/4885THRB 936/4885LMNA 233/4885 |
| US-20190135852-A1 | METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACID | RNGTT, POLR2H, POLR2E | TSHR 551/4885THRB 1506/4885LMNA 214/4885 |
| US-10730904-B2 | Method for liquid-phase synthesis of nucleic acid | RNGTT, POLR2H, POLR2E | TSHR 411/4885THRB 1249/4885LMNA 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.