Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370411 | 0.90 | ACHE (0.67) | ACHEGSTO1ALDH1A1MAPTMEN1 | |
| SCHEMBL9374536 | 0.89 | MEN1 (0.60) | ACHEGSTO1ALDH1A1MAPTMEN1 | |
| SCHEMBL9376371 | 0.88 | LMNA (0.78) | ACHEGSTO1ALDH1A1MAPTMEN1 | |
| SCHEMBL9370547 | 0.88 | LMNA (0.58) | ACHEALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9373340 | 0.87 | ALDH1A1 (0.67) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9371420 | 0.86 | ACHE (0.57) | ACHEGSTO1ALDH1A1MAPTMEN1 | |
| SCHEMBL9370662 | 0.86 | ACHE (0.60) | ACHEGSTO1ALDH1A1MAPTMEN1 | |
| SCHEMBL9376664 | 0.86 | ABL1 (0.63) | GSTO1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9378451 | 0.86 | LMNA (0.61) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL9370494 | 0.86 | LMNA (0.61) | MEN1KMT2ALMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519449-A1 | 2-Amino-4-aryl thiazoles with antiasthmatic and antiinflammatory activities on the respiratory tract | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-12-23 | — | — | EP | disclosed |