Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PHGDH | O43175 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370676 | 0.88 | ROCK1 (0.64) | MAPTALDH1A1MAPK1RAB9ATDP1 | |
| SCHEMBL9371254 | 0.87 | MMP2 (0.54) | MAPTALDH1A1MAPK1SMN1; SMN2MEN1 | |
| SCHEMBL9376122 | 0.87 | KMT2A (0.55) | MAPTMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9371002 | 0.87 | MMP2 (0.61) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9371270 | 0.86 | KCNQ1 (0.49) | MAPTALDH1A1MAPK1RAB9ATDP1 | |
| SCHEMBL9371420 | 0.84 | ACHE (0.57) | MAPTALDH1A1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL9371474 | 0.84 | ACHE (0.55) | MAPTALDH1A1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL9378700 | 0.83 | MAPT (0.65) | MAPTALDH1A1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL9370647 | 0.82 | KMT2A (0.54) | MAPTMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9373421 | 0.81 | SMN1; SMN2 (0.51) | MAPTALDH1A1MAPK1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519449-A1 | 2-Amino-4-aryl thiazoles with antiasthmatic and antiinflammatory activities on the respiratory tract | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-12-23 | — | — | EP | disclosed |