Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706340 | 0.88 | HRH1 (0.47) | FFAR1LMNALOXL2TDP1KDM4E | |
| Hydrochloric Acid SCHEMBL11316021 | 0.86 | HRH1 (0.46) | FFAR1LMNALOXL2TDP1KDM4E | |
| SCHEMBL9135914 | 0.84 | FFAR1 (0.50) | FFAR1LMNATDP1KDM4EHDAC2 | |
| SCHEMBL6573723 | 0.82 | FFAR1 (0.52) | FFAR1LMNALOXL2NPY5RTDP1 | |
| SCHEMBL333186 | 0.80 | FFAR1 (0.70) | FFAR1LMNANPY5RTDP1TBXAS1 | |
| SCHEMBL1677975 | 0.78 | ALDH1A1 (0.63) | FFAR1LMNALOXL2NPY5RTDP1 | |
| SCHEMBL660683 | 0.78 | LOXL2 (0.52) | FFAR1LMNALOXL2NPY5RTDP1 | |
| SCHEMBL4662980 | 0.78 | FFAR1 (0.49) | FFAR1LMNALOXL2NPY5RTDP1 | |
| Hydrochloric Acid SCHEMBL8937697 | 0.78 | FFAR1 (0.68) | FFAR1LMNANPY5RTDP1TBXAS1 | |
| SCHEMBL26111039 | 0.78 | FFAR1 (0.68) | FFAR1LMNANPY5RTDP1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198325-B1 | SUBSTITUTED ANILINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1992-07-15 | — | — | EP | disclosed |
| US-4891429-A | CHEMICAL INTERMEDIATES | HOFFMANN-LA ROCHE INC. (US) | 1990-01-02 | — | — | US | disclosed |
| US-4696930-A | CARDIOVASCULAR DISORDERS, ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1987-09-29 | — | — | US | disclosed |
| EP-0198325-A2 | Substituted aniline derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1986-10-22 | — | — | EP | disclosed |