SCHEMBL9706711

SCHEMBL9706711

CCCc1cc(=O)n(-c2cc(C(=O)O)c(Cl)cc2F)c(=O)n1C

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NOTUM Q6P988 1/20 0.32
KMT2A Q03164 1/20 0.31
BRD9 Q9H8M2 1/20 0.31
BAZ2B Q9UIF8 1/20 0.31
BAZ2A Q9UIF9 1/20 0.31
DRD3 P35462 1/20 0.31
MYC P01106 3/20 0.30
NR4A1 P22736 2/20 0.30
CTSB P07858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9706620 0.91 BRD9 (0.34) HPGDSMN1; SMN2NOTUMKMT2ABRD9
SCHEMBL9706624 0.85 LMNA (0.34) HPGDSMN1; SMN2BAZ2BBAZ2A
SCHEMBL9350427 0.82 NOTUM (0.40) HPGDSMN1; SMN2NOTUMKMT2AMYC
SCHEMBL2976620 0.81 NOTUM (0.34) HPGDSMN1; SMN2NOTUMKMT2AMYC
SCHEMBL24151268 0.80 NOTUM (0.38) HPGDSMN1; SMN2NOTUMKMT2AMYC
SCHEMBL29938165 0.80 NOTUM (0.38) HPGDSMN1; SMN2NOTUMKMT2AMYC
SCHEMBL9521004 0.79 NOTUM (0.31) HPGDSMN1; SMN2NOTUMBRD9
SCHEMBL10578014 0.78 PPOX (0.43) KMT2ATDP1
SCHEMBL9522017 0.77 HPGD (0.33) HPGDSMN1; SMN2NOTUMMYCNR4A1
SCHEMBL9706635 0.77 KDM5A (0.39) HPGDSMN1; SMN2NOTUMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0195346-B1 3-ARYL URACILES AND THEIR USE AS HERBICIDES CIBA-GEIGY AG (CH) 1992-06-24 EP claimed