Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9467207 | 0.91 | AGTR1 (0.35) | AGTR1 | |
| SCHEMBL9706636 | 0.90 | PARP1 (0.33) | — | |
| SCHEMBL9467215 | 0.81 | PARP1 (0.30) | — | |
| SCHEMBL9468065 | 0.76 | AGTR1 (0.43) | AGTR1 | |
| SCHEMBL9706701 | 0.75 | PTGDR2 (0.41) | AGTR1 | |
| SCHEMBL9468038 | 0.75 | PTGDR2 (0.36) | AGTR1 | |
| SCHEMBL9468173 | 0.74 | AGTR1 (0.40) | AGTR1 | |
| SCHEMBL9706628 | 0.74 | AGTR1 (0.38) | AGTR1 | |
| SCHEMBL9467181 | 0.70 | AGTR1 (0.39) | AGTR1 | |
| SCHEMBL9468524 | 0.68 | AGTR1 (0.42) | AGTR1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514217-A1 | Antihypertensive benzofuran derivatives carrying 4-pyrazolylmethyl substituents | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |