Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | BRS3 | P32247 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9467215 | 0.91 | PARP1 (0.30) | PARP1 | |
| SCHEMBL9706631 | 0.90 | AGTR1 (0.39) | — | |
| SCHEMBL9467207 | 0.81 | AGTR1 (0.35) | — | |
| SCHEMBL9706707 | 0.74 | PTGDR2 (0.42) | — | |
| SCHEMBL9706632 | 0.74 | PTGDR2 (0.37) | PPARG | |
| SCHEMBL9468179 | 0.74 | PTGDR2 (0.37) | — | |
| SCHEMBL7314778 | 0.67 | TSHR (0.46) | ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7312950 | 0.67 | KDM4E (0.53) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9468626 | 0.66 | PTGDR2 (0.33) | — | |
| SCHEMBL9468523 | 0.66 | PTGDR2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514217-A1 | Antihypertensive benzofuran derivatives carrying 4-pyrazolylmethyl substituents | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |