Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | BCAT1 | P54687 | 5/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 4/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706635 | 0.91 | KDM5A (0.39) | TSHRHSD17B10MAPTALDH1A1BCAT1 | |
| SCHEMBL9706599 | 0.86 | BAZ2B (0.44) | TSHRHSD17B10MAPTALDH1A1HPGD | |
| SCHEMBL10645885 | 0.85 | MAPT (0.35) | TSHRHSD17B10MAPTALDH1A1BCAT1 | |
| SCHEMBL9706539 | 0.84 | SMN1; SMN2 (0.45) | TSHRHSD17B10MAPTBCAT1BCAT2 | |
| SCHEMBL9586914 | 0.80 | TSHR (0.36) | TSHRHSD17B10MAPTALDH1A1BCAT1 | |
| SCHEMBL3321881 | 0.80 | BCAT1 (0.51) | ALDH1A1BCAT1BCAT2NOTUMSMN1; SMN2 | |
| SCHEMBL9706638 | 0.79 | NOTUM (0.34) | TSHRNOTUMTDP1MYCNR4A1 | |
| SCHEMBL10578943 | 0.77 | PPOX (0.44) | MAPTBCAT1BCAT2TDP1HTT | |
| SCHEMBL9706663 | 0.77 | NOTUM (0.40) | TSHRHSD17B10ALDH1A1NOTUMHPGD | |
| SCHEMBL9706705 | 0.77 | NOTUM (0.37) | TSHRHSD17B10NOTUMHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195346-B1 | 3-ARYL URACILES AND THEIR USE AS HERBICIDES | CIBA-GEIGY AG (CH) | 1992-06-24 | — | — | EP | claimed |