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SCHEMBL9706638

SCHEMBL9706638

CCc1[nH]c(=O)n(-c2cc(C(=O)O)c(Cl)cc2F)c(=O)c1C

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NOTUM Q6P988 3/20 0.34
▸ GNRHR P30968 7/20 0.33
▸ MYC P01106 1/20 0.33
▸ NR4A1 P22736 1/20 0.33
▸ CTSB P07858 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ PPOX P50336 2/20 0.31
▸ ADRA2A P08913 1/20 0.31
▸ CLCN2 P51788 1/20 0.31
▸ TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9706640 0.85 MAPT (0.34) GNRHRPPOX
SCHEMBL9706657 0.82 NOTUM (0.36) NOTUMGNRHRMYCNR4A1CTSB
SCHEMBL9706663 0.82 NOTUM (0.40) NOTUMGNRHRMYCNR4A1CTSB
SCHEMBL9706705 0.82 NOTUM (0.37) NOTUMGNRHRMYCNR4A1CTSB
SCHEMBL9706655 0.79 TSHR (0.34) NOTUMMYCNR4A1CTSBTDP1
SCHEMBL10576736 0.79 PPOX (0.43) TDP1PPOX
SCHEMBL9706650 0.77 NOTUM (0.34) NOTUMMYCNR4A1CTSBTDP1
SCHEMBL9706539 0.77 SMN1; SMN2 (0.45) NOTUMMYCNR4A1CTSBTDP1
SCHEMBL9706614 0.76 SLC9A1 (0.37) NOTUMMYCNR4A1CTSBTDP1
SCHEMBL9706635 0.75 KDM5A (0.39) NOTUMTDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0195346-B1 3-ARYL URACILES AND THEIR USE AS HERBICIDES CIBA-GEIGY AG (CH) 1992-06-24 — — EP claimed