Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545657 | 0.67 | ALDH1A1 (0.32) | TDP1ALDH1A1 | |
| SCHEMBL2178556 | 0.60 | CHRM2 (0.33) | TDP1ALDH1A1HSD17B10 | |
| SCHEMBL3085920 | 0.60 | — | — | |
| SCHEMBL27912787 | 0.60 | — | — | |
| SCHEMBL28818267 | 0.60 | — | — | |
| SCHEMBL11692023 | 0.60 | — | — | |
| SCHEMBL19663841 | 0.60 | — | — | |
| SCHEMBL11053025 | 0.58 | — | — | |
| SCHEMBL7298396 | 0.58 | TDP1 (0.31) | TDP1 | |
| SCHEMBL8026161 | 0.58 | TDP1 (0.42) | TDP1ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992008704-A1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |
| EP-0097464-A1 | Insecticidal compositions having high concentration of active ingredients | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-01-04 | — | — | EP | disclosed |
| EP-0030472-A2 | Carbamoyl sulfides, their preparation, compositions containing them, their use to control insects, intermediates therefor and preparation of said intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-17 | — | — | EP | disclosed |