Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.64 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534771 | 0.79 | AGTR1 (0.75) | AGTR1AGTR2 | |
| SCHEMBL8076001 | 0.78 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL11092792 | 0.78 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL607 | 0.77 | AGTR1 (0.75) | AGTR1AGTR2 | |
| SCHEMBL9089456 | 0.74 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL396 | 0.74 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL9089155 | 0.74 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9086750 | 0.74 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9294548 | 0.74 | AGTR2 (0.62) | AGTR1AGTR2 | |
| SCHEMBL1076 | 0.74 | AGTR1 (0.62) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992015577-A1 | N-SUBSTITUTED (ALPHA-IMIDAZOLYL-TOLUYL) PYRROLE ANGIOTENSIN II ANTAGONISTS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-09-17 | — | — | WO | claimed |