Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | USP1 | O94782 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707459 | 0.94 | KMT2A (0.46) | AGTR1AGTR2PPARGTSHRTP53 | |
| SCHEMBL9708112 | 0.94 | KMT2A (0.42) | AGTR1AGTR2PPARGKMT2AMEN1 | |
| SCHEMBL9707887 | 0.92 | PPARG (0.41) | AGTR1AGTR2PPARGKMT2A | |
| SCHEMBL9708179 | 0.92 | KMT2A (0.42) | AGTR1AGTR2PPARGKMT2A | |
| SCHEMBL9708440 | 0.91 | AGTR1 (0.38) | AGTR1AGTR2PPARGKMT2AMEN1 | |
| SCHEMBL9708195 | 0.91 | PPARG (0.39) | AGTR1AGTR2PPARGKMT2AMEN1 | |
| SCHEMBL9707802 | 0.91 | KMT2A (0.42) | AGTR1AGTR2PPARGTSHRKMT2A | |
| SCHEMBL9708435 | 0.91 | PPARG (0.39) | AGTR1AGTR2PPARGKMT2A | |
| SCHEMBL9707917 | 0.91 | KMT2A (0.41) | AGTR1AGTR2PPARGKMT2AALDH1A1 | |
| SCHEMBL9708548 | 0.90 | PPARG (0.38) | AGTR1AGTR2PPARGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |