Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707539 | 0.95 | AGTR1 (0.40) | AGTR1AGTR2PPARGKMT2A | |
| SCHEMBL9707749 | 0.92 | AGTR1 (0.38) | AGTR1AGTR2PPARGKMT2A | |
| SCHEMBL9708435 | 0.92 | PPARG (0.39) | AGTR1AGTR2PPARGKMT2AKCNH2 | |
| SCHEMBL9707805 | 0.91 | AGTR1 (0.43) | AGTR1AGTR2PPARGKMT2A | |
| SCHEMBL9708749 | 0.91 | KMT2A (0.44) | AGTR1AGTR2PPARGKMT2A | |
| SCHEMBL9707596 | 0.90 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL9707676 | 0.90 | AGTR1 (0.46) | AGTR1AGTR2PPARG | |
| SCHEMBL9708661 | 0.90 | AGTR1 (0.38) | AGTR1AGTR2PPARG | |
| SCHEMBL9707562 | 0.90 | AGTR1 (0.39) | AGTR1AGTR2PPARGKMT2A | |
| SCHEMBL9708253 | 0.89 | PDE5A (0.36) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |