Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.52 |
| ▸ | TUBB | P07437 | 3/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL722969 | 0.98 | PTGS2 (0.67) | PTGS2HTR2AHTR2CHTR2BACHE | |
| SCHEMBL15271424 | 0.83 | PTGS2 (0.50) | PTGS2HTR2AHTR2CHTR2BACHE | |
| SCHEMBL3127096 | 0.82 | HTR2A (0.64) | PTGS2HTR2AHTR2CHTR2BACHE | |
| SCHEMBL4464142 | 0.80 | HTR2A (0.75) | PTGS2HTR2AHTR2CHTR2BACHE | |
| SCHEMBL8910416 | 0.80 | PTGS2 (0.70) | PTGS2HTR2AHTR2CHTR2BACHE | |
| SCHEMBL9085046 | 0.80 | PTGS2 (0.47) | PTGS2HTR2AHTR2CHTR2BACHE | |
| SCHEMBL21980854 | 0.80 | PTGS2 (0.47) | PTGS2HTR2AHTR2CHTR2BTUBB4A | |
| SCHEMBL6780613 | 0.79 | HTR2A (0.60) | PTGS2HTR2AHTR2CHTR2BACHE | |
| SCHEMBL8067442 | 0.78 | TUBB4A (0.54) | PTGS2HTR2ATUBB4ATUBBTUBA3C | |
| Bromide SCHEMBL28463593 | 0.78 | PTGS2 (0.46) | PTGS2HTR2AHTR2CHTR2BTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10952975-B2 | Compositions and methods for treatment of cancer | TERMAN DAVID S (US) | 2021-03-23 | — | — | US | disclosed |
| US-20200297658-A1 | Compositions and Methods for Treatment of Cancer | TERMAN DAVID S (US) | 2020-09-24 | — | — | US | disclosed |
| WO-1992016486-A1 | SUBSTITUTED DIPHENYLETHYLENES AND ANALOGUES OR DERIVATIVES THEREOF | ASTON MOLECULES LIMITED (GB) | 1992-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200297658-A1 | Compositions and Methods for Treatment of Cancer | CD47, VEGFA, VHL | PTGS2 819/4885HTR2A 3533/4885HTR2C 4304/4885 |
| US-10952975-B2 | Compositions and methods for treatment of cancer | CD47, VEGFA, VHL | PTGS2 819/4885HTR2A 3533/4885HTR2C 4304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.