Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9708831 | 0.94 | HPGD (0.39) | DPP4BRAFTSHRMAPTLMNA | |
| SCHEMBL9707549 | 0.91 | ADORA3 (0.39) | — | |
| SCHEMBL9708607 | 0.91 | DPP4 (0.38) | DPP4BRAFPIK3CGTSHRMAPT | |
| SCHEMBL9707866 | 0.91 | AGTR1 (0.35) | — | |
| SCHEMBL9707684 | 0.91 | ADORA1 (0.37) | — | |
| SCHEMBL9708272 | 0.91 | TSHR (0.42) | TSHRMAPTALOX15HSD17B10 | |
| SCHEMBL9707571 | 0.89 | ALDH1A1 (0.38) | DPP4BRAFPIK3CGTSHRMAPT | |
| SCHEMBL9708736 | 0.89 | AGTR1 (0.42) | TSHRALOX15HSD17B10 | |
| SCHEMBL9708380 | 0.88 | TSHR (0.40) | DPP4BRAFPIK3CGTSHRMAPT | |
| SCHEMBL9708330 | 0.88 | ADORA3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |