SCHEMBL9708626

SCHEMBL9708626

O=C(O)C1(C(=O)O)COC2(CCC3(CC2)OCC(C(=O)O)(C(=O)O)CO3)OC1

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL818086 0.88 POLB (0.36)
SCHEMBL9709063 0.88 POLB (0.36)
SCHEMBL10652438 0.84 KDM4E (0.31)
SCHEMBL16817547 0.77 ALDH1A1 (0.36) FFAR3
SCHEMBL9708741 0.74 FFAR3 (0.38) FFAR3
SCHEMBL7093051 0.72
SCHEMBL14742645 0.71 FFAR3 (0.32) FFAR3
SCHEMBL9090517 0.71 TSHR (0.34)
SCHEMBL9092010 0.69 ESR1 (0.34)
SCHEMBL9709078 0.69 LMNA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0220034-B1 MALONATE DERIVATIVES USEFUL AS LIGHT STABILIZERS FOR PLASTICS ICI AMERICAS INC. (US) 1992-06-24 EP claimed
US-4701485-A Malonate-based light stabilizers for plastics ICI AMERICAS INC. (US) 1987-10-20 US claimed
EP-0220034-A2 Malonate derivatives useful as light stabilizers for plastics ICI AMERICAS INC. (US) 1987-04-29 EP claimed
EP-0220034-B1 MALONATE DERIVATIVES USEFUL AS LIGHT STABILIZERS FOR PLASTICS ICI AMERICAS INC. (US) 1992-06-24 EP disclosed
US-4701485-A Malonate-based light stabilizers for plastics ICI AMERICAS INC. (US) 1987-10-20 US disclosed
EP-0220034-A2 Malonate derivatives useful as light stabilizers for plastics ICI AMERICAS INC. (US) 1987-04-29 EP disclosed