Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.48 |
| ▸ | PPARG | P37231 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9708041 | 0.98 | AGTR1 (0.51) | AGTR1AGTR2PPARGKDM4EALDH1A1 | |
| SCHEMBL9708634 | 0.95 | KDM4E (0.46) | AGTR1AGTR2PPARGKDM4EALDH1A1 | |
| SCHEMBL9707728 | 0.91 | AGTR1 (0.54) | AGTR1AGTR2PPARG | |
| SCHEMBL9708070 | 0.90 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9708699 | 0.90 | AGTR1 (0.45) | AGTR1AGTR2PPARG | |
| SCHEMBL9708532 | 0.90 | TRPC4 (0.46) | AGTR1AGTR2ALDH1A1 | |
| SCHEMBL9707808 | 0.89 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9708200 | 0.89 | AGTR1 (0.51) | AGTR1AGTR2PPARG | |
| SCHEMBL9708365 | 0.88 | AGTR1 (0.48) | AGTR1AGTR2PPARGALDH1A1 | |
| SCHEMBL9707950 | 0.88 | AGTR1 (0.48) | AGTR1AGTR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |