Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 9/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3523036 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL7073387 | 0.70 | KDM4E (0.71) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL5034828 | 0.69 | PGR (0.49) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL12417556 | 0.69 | KDM4E (0.54) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL30973139 | 0.68 | KDM4E (0.83) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL4207661 | 0.68 | PGR (0.53) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL4704892 | 0.66 | PGR (0.59) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL13747310 | 0.66 | PGR (0.47) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL6470321 | 0.66 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL1394706 | 0.66 | ALDH1A1 (0.97) | ALDH1A1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020263164-A1 | COMPOUNDS TARGETING DUAL G-QUADRUPLEX DNA AND STAT3 | SABOURI NASIM (SE) | 2020-12-30 | — | — | WO | disclosed |
| EP-0515684-A1 | INHIBITOR OF DENATURED LDL FORMATION | Chugai Seiyaku Kabushiki Kaisha (JP) | 1992-12-02 | — | — | EP | disclosed |