Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709176 | 0.77 | CNR2 (0.43) | CYP1A2MMP2HPGDALDH1A1CYP2C19 | |
| SCHEMBL9709042 | 0.74 | CYP1A2 (0.46) | CYP1A2ALDH1A1 | |
| SCHEMBL9604373 | 0.74 | NPY1R (0.42) | HDAC2HDAC8HDAC6CYP1A2NPC1 | |
| SCHEMBL1903649 | 0.69 | HDAC2 (0.54) | HDAC2HDAC8HDAC6RAB9AHDAC1 | |
| SCHEMBL21587872 | 0.69 | HDAC2 (0.54) | HDAC2HDAC8HDAC6RAB9AHDAC1 | |
| SCHEMBL24533878 | 0.67 | MMP2 (0.58) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL24533867 | 0.67 | MMP2 (0.58) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL16359253 | 0.67 | HDAC2 (0.53) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL9708917 | 0.67 | CNR2 (0.40) | CYP1A2ALDH1A1CYP2C19CNR2 | |
| SCHEMBL16908006 | 0.66 | HDAC2 (0.51) | HDAC2HDAC8HDAC6RAB9AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020665-A1 | THIAZOLIDINE DERIVATIVES AND THEIR USE IN THERAPY | GLAXO GROUP LIMITED (GB) | 1992-11-26 | — | — | WO | disclosed |