Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 7/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.60 |
| ▸ | FABP4 | P15090 | 1/20 | 0.59 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.52 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.50 |
| ▸ | ACLY | P53396 | 1/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.49 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10171027 | 0.91 | AKR1C3 (0.70) | AKR1C3AKR1C2MAPTGFERNGLY1 | |
| SCHEMBL11604475 | 0.86 | AKR1C3 (0.62) | AKR1C3AKR1C2MAPTFABP4MPO | |
| SCHEMBL13890899 | 0.85 | AKR1C3 (0.59) | AKR1C3AKR1C2MAPTGFERNGLY1 | |
| SCHEMBL17291893 | 0.84 | MAPT (0.67) | AKR1C3AKR1C2MAPTGFERNGLY1 | |
| SCHEMBL28472949 | 0.82 | AKR1C3 (0.64) | AKR1C3AKR1C2MAPTGFERNGLY1 | |
| SCHEMBL351705 | 0.81 | MAPT (0.79) | AKR1C3AKR1C2MAPTGFERNGLY1 | |
| SCHEMBL4158603 | 0.81 | FABP4 (0.71) | AKR1C3AKR1C2MAPTFABP4TAS2R14 | |
| SCHEMBL2476797 | 0.81 | MAPT (0.63) | AKR1C3AKR1C2MAPTGFERNGLY1 | |
| SCHEMBL1415595 | 0.80 | AKR1C3 (0.67) | AKR1C3AKR1C2MAPTGFERNGLY1 | |
| SCHEMBL384593 | 0.80 | FABP4 (0.65) | AKR1C3AKR1C2FABP4MPOGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11839144-B2 | Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-12-05 | — | — | US | disclosed |
| US-11839144-B2 | Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-12-05 | — | — | US | disclosed |
| US-11839144-B2 | Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-12-05 | — | — | US | disclosed |
| US-20210217973-A1 | Tetradentate Cyclometalated Platinum Complexes Containing 9,10-Dihydroacridine And Its Analogues | UNIV ARIZONA STATE (US) | 2021-07-15 | — | — | US | disclosed |
| US-20210217973-A1 | Tetradentate Cyclometalated Platinum Complexes Containing 9,10-Dihydroacridine And Its Analogues | UNIV ARIZONA STATE (US) | 2021-07-15 | — | — | US | disclosed |
| US-11011712-B2 | Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-05-18 | — | — | US | disclosed |
| US-11011712-B2 | Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-05-18 | — | — | US | disclosed |
| US-20180226593-A1 | Tetradentate Cyclometalated Platinum Complexes Containing 9,10-Dihydroacridine And Its Analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2018-08-09 | — | — | US | disclosed |
| US-20180226593-A1 | Tetradentate Cyclometalated Platinum Complexes Containing 9,10-Dihydroacridine And Its Analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2018-08-09 | — | — | US | disclosed |
| US-9941479-B2 | Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-04-10 | — | — | US | disclosed |
| US-9941479-B2 | Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-04-10 | — | — | US | disclosed |
| US-9941479-B2 | Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-04-10 | — | — | US | disclosed |
| US-20150349279-A1 | Tetradentate Cyclometalated Platinum Complexes Containing 9,10-Dihydroacridine And Its Analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2015-12-03 | — | — | US | disclosed |
| US-20150349279-A1 | Tetradentate Cyclometalated Platinum Complexes Containing 9,10-Dihydroacridine And Its Analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2015-12-03 | — | — | US | disclosed |
| US-20150349279-A1 | Tetradentate Cyclometalated Platinum Complexes Containing 9,10-Dihydroacridine And Its Analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2015-12-03 | — | — | US | disclosed |
| EP-0471516-A1 | Tricyclic heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180226593-A1 | Tetradentate Cyclometalated Platinum Complexes Containing 9,10-Dihydroacridine And Its Analogues | DPYD, DCTD, TYMP | AKR1C3 3700/4885AKR1C2 3544/4885MAPT 538/4885 |
| US-11011712-B2 | Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues | DPYD, DCTD, TYMP | AKR1C3 3700/4885AKR1C2 3544/4885MAPT 538/4885 |
| US-20210217973-A1 | Tetradentate Cyclometalated Platinum Complexes Containing 9,10-Dihydroacridine And Its Analogues | DPYD, DCTD, TYMP | AKR1C3 3700/4885AKR1C2 3544/4885MAPT 538/4885 |
| US-20150349279-A1 | Tetradentate Cyclometalated Platinum Complexes Containing 9,10-Dihydroacridine And Its Analogues | DPYD, DCTD, TYMP | AKR1C3 3700/4885AKR1C2 3544/4885MAPT 538/4885 |
| US-11839144-B2 | Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues | DPYD, DCTD, TYMP | AKR1C3 3700/4885AKR1C2 3544/4885MAPT 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.