Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BRS3 | P32247 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9604373 | 0.90 | NPY1R (0.42) | CNR2CYP1A2GAACA1CA2 | |
| SCHEMBL9709146 | 0.77 | HDAC2 (0.40) | CNR2CYP1A2CYP2C19HPGDALDH1A1 | |
| SCHEMBL4153733 | 0.69 | HPGD (0.79) | HPGDGAACA1CA2CA5A | |
| SCHEMBL21560529 | 0.66 | CHRNA1 (0.73) | BRS3KMT2AMMP2 | |
| SCHEMBL21560530 | 0.66 | CHRNA1 (0.73) | BRS3KMT2AMMP2 | |
| SCHEMBL9709042 | 0.65 | CYP1A2 (0.46) | CYP1A2POLBALDH1A1 | |
| SCHEMBL10635162 | 0.64 | POLB (0.61) | CYP2D6CYP2C9CYP2C19CA1CA2 | |
| SCHEMBL9192833 | 0.64 | POLB (0.61) | CYP2D6CYP2C9CYP2C19CA1CA2 | |
| SCHEMBL9640676 | 0.64 | CYP1A2 (0.45) | CYP1A2 | |
| SCHEMBL9640267 | 0.64 | CYP1A2 (0.45) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020665-A1 | THIAZOLIDINE DERIVATIVES AND THEIR USE IN THERAPY | GLAXO GROUP LIMITED (GB) | 1992-11-26 | — | — | WO | claimed |