Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 3/20 | 0.55 |
| ▸ | NSD2 | O96028 | 3/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PTPRC | P08575 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | S100A4 | P26447 | 5/20 | 0.47 |
| ▸ | CDC25B | P30305 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17965509 | 0.84 | PTPRC (0.47) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL1750489 | 0.79 | MEN1 (0.58) | TDP2PLCG1CES1MEN1THRB | |
| SCHEMBL1749823 | 0.77 | GAA (0.50) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL5915065 | 0.77 | TDP2 (0.81) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL29746876 | 0.75 | GAA (0.78) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL1899280 | 0.75 | PTPRC (0.88) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL29566445 | 0.75 | PTPRC (0.88) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL1103717 | 0.75 | GAA (0.78) | TDP2NSD2PAX8ABL1PLCG1 | |
| Bromide SCHEMBL28836578 | 0.74 | PTPRC (0.84) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL9267635 | 0.73 | TDP2 (0.74) | TDP2NSD2PAX8ABL1PLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471516-A1 | Tricyclic heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-19 | — | — | EP | disclosed |