Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | FABP7 | O15540 | 1/20 | 0.30 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015851 | 0.82 | TSHR (0.42) | CYP1A2TSHRCYP2C19ALDH1A1 | |
| SCHEMBL9709460 | 0.82 | CYP1A2 (0.43) | CYP1A2TSHRCYP2C19POLBALDH1A1 | |
| SCHEMBL10435405 | 0.79 | POLB (0.39) | CYP1A2TSHRCYP2C19POLBALDH1A1 | |
| SCHEMBL755810 | 0.78 | KMT2A (0.45) | CYP1A2TSHRCASP3CA1CA2 | |
| SCHEMBL4906912 | 0.77 | CYP1A2 (0.41) | CYP1A2TSHRCYP2C19POLBMAPT | |
| SCHEMBL2890843 | 0.76 | CYP1A2 (0.39) | CYP1A2TSHRCYP2C19POLBALDH1A1 | |
| SCHEMBL653721 | 0.75 | POLB (0.38) | CYP1A2TSHRCYP2C19POLB | |
| SCHEMBL11006773 | 0.74 | MMP1 (0.39) | CYP1A2TSHRPOLBMAPTALDH1A1 | |
| SCHEMBL10937190 | 0.74 | TUBB4A (0.43) | MAPTALDH1A1HTTFABP7FABP5 | |
| SCHEMBL28152768 | 0.73 | KMT2A (0.39) | CASP3FABP7FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951746-B1 | SOLUTION-PHASE SYNTHESIS OF LEUPROLIDE AND ITS INTERMEDIATES | NANOKEM S A (UY) | 2010-03-17 | — | — | EP | disclosed |