SCHEMBL9709523

SCHEMBL9709523

O=C(/C=C/C(=O)Oc1ccc(C2CCCCC2)cc1)Oc1ccc(C2CCCCC2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.48
MEN1 O00255 1/20 0.48
NPC1 O15118 1/20 0.48
POLB P06746 1/20 0.48
RAB9A P51151 1/20 0.48
BLM P54132 1/20 0.48
GPR35 Q9HC97 1/20 0.48
HDAC8 Q9BY41 2/20 0.46
HDAC6 Q9UBN7 2/20 0.46
HDAC1 Q13547 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
HAO1 Q9UJM8 2/20 0.44
HTT P42858 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
HRH3 Q9Y5N1 2/20 0.43
FAAH O00519 1/20 0.43
ACMSD Q8TDX5 2/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2582818 0.86 THRB (0.45) KMT2AMEN1NPC1POLBRAB9A
SCHEMBL238310 0.85 HDAC8 (0.49) KMT2AMEN1NPC1POLBRAB9A
SCHEMBL10528691 0.85 KMT2A (0.58) KMT2AMEN1NPC1POLBRAB9A
SCHEMBL10528689 0.85 KMT2A (0.58) KMT2AMEN1NPC1POLBRAB9A
SCHEMBL7510922 0.84 HAO1 (0.49) KMT2AMEN1NPC1POLBRAB9A
SCHEMBL22490430 0.83 TRPM8 (0.57) KMT2AMEN1NPC1POLBRAB9A
SCHEMBL1790802 0.82 MAPT (0.50) KMT2APOLBHDAC8HDAC6HDAC1
SCHEMBL5185070 0.81 KMT2A (0.70) KMT2AMEN1POLBHDAC8HDAC6
SCHEMBL233920 0.81 SMN1; SMN2 (0.45) KMT2AMEN1NPC1POLBRAB9A
SCHEMBL1790363 0.80 LMNA (0.52) KMT2AMEN1POLBHDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0244835-B1 LANGMUIR-BLODGETT ULTRATHIN MEMBRANE OF POLYFUMURATE NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1992-08-26 EP claimed
EP-0233299-B1 OPTICAL RESIN AND PROCESS FOR PREPARING THE SAME NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-03-13 EP claimed
US-4907038-A Langmuir Blodgett ultrathin membrane of polyfumarate NIPPON OIL AND FATS CO., LTD. (JP) 1990-03-06 US claimed
US-4855374-A Optical resin from diallyl esters NIPPON OIL AND FATS CO., LTD. (JP) 1989-08-08 US claimed
EP-0244835-A2 Langmuir-Blodgett ultrathin membrane of polyfumurate NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-11-11 EP claimed
EP-0233299-A1 Optical resin and process for preparing the same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-08-26 EP claimed
EP-0233299-B1 OPTICAL RESIN AND PROCESS FOR PREPARING THE SAME NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-03-13 EP disclosed
US-4855374-A Optical resin from diallyl esters NIPPON OIL AND FATS CO., LTD. (JP) 1989-08-08 US disclosed
EP-0233299-A1 Optical resin and process for preparing the same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-08-26 EP disclosed