Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.46 |
| ▸ | NQO2 | P16083 | 4/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12014805 | 0.82 | NQO2 (0.51) | HPGDSNQO2MCHR1PDE3BPDE3A | |
| SCHEMBL4181276 | 0.77 | PDE3B (0.46) | HPGDSNQO2MCHR1PDE3BPDE3A | |
| SCHEMBL1886039 | 0.77 | KDM4E (0.51) | HPGDSNQO2MCHR1PDE3BPDE3A | |
| SCHEMBL1883218 | 0.75 | HPGDS (0.48) | HPGDSNQO2MCHR1PDE3BPDE3A | |
| SCHEMBL4717115 | 0.74 | ACHE (0.44) | HPGDSNQO2MCHR1PDE3BPDE3A | |
| SCHEMBL4714235 | 0.73 | CNR2 (0.49) | HPGDSPDE3BPDE3AALDH1A1MEN1 | |
| SCHEMBL9709536 | 0.71 | ALDH1A1 (0.51) | HPGDSNQO2MCHR1PDE3BPDE3A | |
| SCHEMBL25367145 | 0.71 | MEN1 (0.47) | ALDH1A1MEN1HPGDKMT2AKDM4E | |
| SCHEMBL873240 | 0.71 | MCHR1 (0.70) | NQO2MCHR1PDE3BPDE3AALDH1A1 | |
| SCHEMBL13255543 | 0.71 | DRD4 (0.52) | NQO2MCHR1PDE3BPDE3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |