Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18282350 | 0.90 | TSHR (0.53) | NAAAALDH1A1TDP1MAPK1L3MBTL1 | |
| SCHEMBL20057183 | 0.89 | NAAA (0.46) | NAAAALDH1A1TDP1MAPK1L3MBTL1 | |
| SCHEMBL29441988 | 0.88 | L3MBTL1 (0.55) | ALDH1A1TDP1MAPK1L3MBTL1TSHR | |
| SCHEMBL26813230 | 0.88 | NAAA (0.45) | NAAAALDH1A1TDP1MAPK1L3MBTL1 | |
| SCHEMBL21068656 | 0.88 | NAAA (0.45) | NAAAALDH1A1TDP1MAPK1L3MBTL1 | |
| SCHEMBL1934676 | 0.87 | ALDH1A1 (0.56) | NAAAALDH1A1TDP1MAPK1L3MBTL1 | |
| SCHEMBL21068327 | 0.86 | NAAA (0.44) | NAAAALDH1A1TDP1MAPK1L3MBTL1 | |
| SCHEMBL21068903 | 0.86 | NAAA (0.44) | NAAAALDH1A1TDP1MAPK1L3MBTL1 | |
| SCHEMBL21458941 | 0.86 | NAAA (0.44) | NAAAALDH1A1TDP1MAPK1L3MBTL1 | |
| SCHEMBL21069059 | 0.86 | NAAA (0.44) | NAAAALDH1A1TDP1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153214-A | Treating cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0493324-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | disclosed |