Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | GLA | P06280 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709721 | 0.90 | KDM4E (0.54) | MEN1KMT2AHTTGAARAB9A | |
| SCHEMBL3924808 | 0.90 | MEN1 (0.52) | MEN1KMT2AHTTGAARAB9A | |
| SCHEMBL28499306 | 0.84 | HTT (0.55) | MEN1KMT2AHTTGAARAB9A | |
| SCHEMBL3924829 | 0.83 | HTT (0.75) | MEN1KMT2AHTTGAARAB9A | |
| SCHEMBL27299051 | 0.81 | KMT2A (0.49) | MEN1KMT2AHTTGAARAB9A | |
| SCHEMBL9709865 | 0.81 | ALDH1A1 (0.51) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL27837493 | 0.80 | MEN1 (0.52) | MEN1KMT2AHTTGAARAB9A | |
| SCHEMBL15919362 | 0.76 | ACP1 (0.56) | MEN1KMT2AHTTGAARAB9A | |
| SCHEMBL13742891 | 0.76 | GAA (0.74) | MEN1KMT2AHTTGAARAB9A | |
| SCHEMBL17981164 | 0.75 | PTPN1 (0.56) | MEN1KMT2AHTTGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |