Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709565 | 0.81 | MEN1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL9907539 | 0.78 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1TP53MAPTKDM4E | |
| SCHEMBL28294971 | 0.77 | RAB9A (0.50) | ALDH1A1TP53NPC1RAB9ACYP1A2 | |
| SCHEMBL4908883 | 0.77 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDNPC1CYP1A2 | |
| SCHEMBL17047601 | 0.76 | HSD17B2 (0.46) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL9709715 | 0.76 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1TP53MAPTKDM4E | |
| SCHEMBL24829712 | 0.75 | HDAC1 (0.48) | RAB9ACYP1A2 | |
| SCHEMBL1008601 | 0.75 | MAPT (0.48) | ALDH1A1L3MBTL1MAPTKDM4ENPC1 | |
| SCHEMBL753526 | 0.75 | PTGER4 (0.57) | CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9709721 | 0.72 | KDM4E (0.54) | ALDH1A1KDM4EHPGDHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |