Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGT | P01019 | 2/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709627 | 0.94 | AGTR1 (0.38) | AGTAGTR1AGTR2 | |
| SCHEMBL9709746 | 0.87 | AGTR1 (0.39) | AGTAGTR1AGTR2 | |
| SCHEMBL9709767 | 0.79 | AGT (0.39) | AGTAGTR1AGTR2 | |
| SCHEMBL9709716 | 0.77 | AGT (0.41) | AGTAGTR1AGTR2 | |
| SCHEMBL9709690 | 0.76 | AGTR1 (0.44) | AGTAGTR1AGTR2 | |
| SCHEMBL9709709 | 0.74 | AGTR1 (0.38) | AGTAGTR1AGTR2 | |
| SCHEMBL9709712 | 0.73 | AGT (0.41) | AGTAGTR1AGTR2 | |
| SCHEMBL9709702 | 0.72 | AGTR1 (0.42) | AGTAGTR1AGTR2 | |
| SCHEMBL9709871 | 0.71 | AGT (0.45) | AGTAGTR1AGTR2 | |
| SCHEMBL27360548 | 0.70 | AGTR1 (0.41) | AGTAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |