Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.44 |
| ▸ | CD38 | P28907 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709869 | 0.88 | AGTR1 (0.43) | AGTR1AGTR2CD38BDKRB1LTB4R2 | |
| SCHEMBL9709600 | 0.86 | AGTR1 (0.48) | AGTR1AGTR2CD38MEN1KMT2A | |
| SCHEMBL9709700 | 0.83 | VCP (0.52) | AGTR1AGTR2CD38MEN1KMT2A | |
| SCHEMBL3058636 | 0.83 | CD38 (0.56) | CD38BDKRB1LTB4R2 | |
| SCHEMBL9710208 | 0.83 | AGTR1 (0.47) | AGTR1AGTR2CD38MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9494706 | 0.82 | CD38 (0.55) | CD38BDKRB1LTB4R2 | |
| SCHEMBL3058746 | 0.81 | AGTR1 (0.50) | AGTR1AGTR2MEN1KMT2A | |
| SCHEMBL9709608 | 0.81 | CD38 (0.50) | AGTR1AGTR2CD38MEN1KMT2A | |
| SCHEMBL9709814 | 0.81 | CD38 (0.55) | CD38MEN1KMT2ABDKRB1 | |
| SCHEMBL9709886 | 0.80 | AGTR1 (0.46) | AGTR1AGTR2CD38MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |