Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 8/20 | 0.51 |
| ▸ | CD38 | P28907 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709814 | 0.93 | CD38 (0.55) | VCPPPARGCD38ALDH1A1POLB | |
| SCHEMBL3058636 | 0.89 | CD38 (0.56) | CD38BDKRB1 | |
| Hydrochloric Acid SCHEMBL9494706 | 0.89 | CD38 (0.55) | CD38BDKRB1 | |
| SCHEMBL9709608 | 0.87 | CD38 (0.50) | VCPCD38MEN1KMT2ABDKRB1 | |
| SCHEMBL9709600 | 0.83 | AGTR1 (0.48) | VCPCD38MEN1KMT2AGPR35 | |
| SCHEMBL9709621 | 0.83 | AGTR1 (0.44) | CD38MEN1KMT2ABDKRB1GPR35 | |
| SCHEMBL9709799 | 0.83 | CD38 (0.47) | VCPPPARGCD38BDKRB1AGTR1 | |
| SCHEMBL9709749 | 0.82 | CD38 (0.64) | PPARGCD38BDKRB1 | |
| SCHEMBL9709723 | 0.81 | AGTR1 (0.47) | PPARGALDH1A1L3MBTL1AGTR1AGTR2 | |
| SCHEMBL9709971 | 0.81 | CD38 (0.52) | VCPCD38BDKRB1AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |