Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | USP1 | O94782 | 2/20 | 0.34 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709637 | 0.86 | PDE4A (0.44) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| SCHEMBL9709866 | 0.83 | AGTR1 (0.47) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| SCHEMBL9709589 | 0.80 | AGTR1 (0.49) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| SCHEMBL9709803 | 0.78 | AGTR1 (0.41) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| SCHEMBL9709617 | 0.78 | AGTR1 (0.36) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| SCHEMBL9709611 | 0.78 | AGTR1 (0.36) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL9702612 | 0.77 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9709905 | 0.77 | USP1 (0.40) | AGTR1AGTR2USP1WDR48 | |
| SCHEMBL9709925 | 0.77 | PDE4A (0.42) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| SCHEMBL9709842 | 0.76 | AGTR1 (0.38) | AGTR1AGTR2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | claimed |