Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CASP2 | P42575 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709748 | 0.85 | KMT2A (0.56) | MEN1KMT2AHTTKDM4ERAD52 | |
| SCHEMBL9709726 | 0.79 | CD38 (0.50) | LMNAMEN1KMT2AHTTKDM4E | |
| SCHEMBL3924829 | 0.76 | HTT (0.75) | LMNAMEN1KMT2AHTTKDM4E | |
| SCHEMBL13587071 | 0.74 | CA12 (0.42) | LMNAMEN1KMT2ACA12CA1 | |
| SCHEMBL12931843 | 0.74 | SMN1; SMN2 (0.45) | MEN1KMT2AHTTBRD9LCK | |
| SCHEMBL10329947 | 0.73 | SMN1; SMN2 (0.41) | MEN1KMT2AHTTBRD9LCK | |
| SCHEMBL20838504 | 0.72 | KDM4E (0.42) | KMT2AHTTCA12CA1CA9 | |
| SCHEMBL29468050 | 0.72 | LCK (0.43) | MEN1KMT2ACA12CA1CA9 | |
| SCHEMBL31093877 | 0.71 | LCK (0.47) | CA12CA1CA9BRD9LCK | |
| SCHEMBL4568018 | 0.71 | NLRP3 (0.55) | LMNATP53ALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |