Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 14/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3051435 | 0.88 | CD38 (0.60) | CD38CYP3A4KCNH2 | |
| SCHEMBL3058636 | 0.87 | CD38 (0.56) | CD38BDKRB1 | |
| Hydrochloric Acid SCHEMBL9494706 | 0.86 | CD38 (0.55) | CD38BDKRB1 | |
| SCHEMBL9363742 | 0.82 | CD38 (0.69) | CD38CYP3A4KCNH2 | |
| SCHEMBL9709700 | 0.82 | VCP (0.52) | CD38BDKRB1PPARG | |
| SCHEMBL9709814 | 0.79 | CD38 (0.55) | CD38BDKRB1PPARG | |
| SCHEMBL9709608 | 0.79 | CD38 (0.50) | CD38BDKRB1 | |
| SCHEMBL9709799 | 0.79 | CD38 (0.47) | CD38BDKRB1PPARG | |
| SCHEMBL9494718 | 0.78 | ACP1 (0.54) | CD38BDKRB1 | |
| SCHEMBL20680363 | 0.78 | CD38 (1.00) | CD38CYP3A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | claimed |
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |