Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 3/20 | 0.47 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.42 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709971 | 0.93 | CD38 (0.52) | CD38BDKRB1LTB4R2VCPAGTR2 | |
| SCHEMBL3058636 | 0.84 | CD38 (0.56) | CD38BDKRB1LTB4R2 | |
| SCHEMBL9709886 | 0.84 | AGTR1 (0.46) | CD38VCPAGTR2AGTR1 | |
| Hydrochloric Acid SCHEMBL9494706 | 0.83 | CD38 (0.55) | CD38BDKRB1LTB4R2 | |
| SCHEMBL9709869 | 0.83 | AGTR1 (0.43) | CD38BDKRB1LTB4R2VCPAGTR2 | |
| SCHEMBL9709700 | 0.83 | VCP (0.52) | CD38BDKRB1VCPAGTR2AGTR1 | |
| SCHEMBL9709660 | 0.82 | AGTR1 (0.45) | LTB4R2AGTR2AGTR1 | |
| SCHEMBL9709608 | 0.80 | CD38 (0.50) | CD38BDKRB1LTB4R2VCPAGTR2 | |
| SCHEMBL9709814 | 0.80 | CD38 (0.55) | CD38BDKRB1VCPPPARG | |
| SCHEMBL9709749 | 0.79 | CD38 (0.64) | CD38BDKRB1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | claimed |
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |