Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT1 | P34896 | 8/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | SHMT2 | P34897 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709763 | 0.82 | EIF4E (0.47) | CYP1A2KDM4ENPC1RAB9AEIF4E | |
| SCHEMBL9709774 | 0.74 | SHMT1 (0.48) | SHMT1PRKD3PRKCGPRKCBIL1R1 | |
| SCHEMBL9709590 | 0.72 | CYP1A2 (0.42) | CYP1A2KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL9709798 | 0.70 | PRKD3 (0.40) | SHMT1PRKD3PRKCGPRKCBIL1R1 | |
| SCHEMBL21560101 | 0.69 | SHMT1 (0.72) | SHMT1PRKD3PRKCGPRKCBIL1R1 | |
| SCHEMBL21560027 | 0.69 | SHMT1 (0.72) | SHMT1PRKD3PRKCGPRKCBIL1R1 | |
| SCHEMBL21560109 | 0.69 | SHMT1 (0.72) | SHMT1PRKD3PRKCGPRKCBIL1R1 | |
| SCHEMBL30775593 | 0.69 | PRKD3 (0.62) | SHMT1PRKD3PRKCGPRKCBIL1R1 | |
| SCHEMBL22637490 | 0.69 | PRKD3 (0.62) | SHMT1PRKD3PRKCGPRKCBIL1R1 | |
| SCHEMBL20241895 | 0.67 | SHMT1 (0.54) | SHMT1PRKD3PRKCGPRKCBIL1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489660-A1 | Utilization of thiazolylalkoxyacrylates for the preparation of insecticidal and/or acaricidal compositions | ROUSSEL-UCLAF (FR) | 1992-06-10 | — | — | EP | disclosed |