Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.69 |
| ▸ | TSHR | P16473 | 6/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5540540 | 0.92 | ALDH1A1 (0.58) | ALDH1A1TSHRALOX15HSD17B10MAPK1 | |
| SCHEMBL65261 | 0.83 | ALDH1A1 (1.00) | ALDH1A1TSHRALOX15HSD17B10MAPK1 | |
| SCHEMBL28076670 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRALOX15HSD17B10MAPK1 | |
| SCHEMBL2058932 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRALOX15HSD17B10MAPK1 | |
| Hydrochloric Acid SCHEMBL2443748 | 0.79 | ALDH1A1 (0.92) | ALDH1A1TSHRALOX15HSD17B10MAPK1 | |
| Ammonia Solution, Strong SCHEMBL27868785 | 0.79 | ALDH1A1 (0.92) | ALDH1A1TSHRALOX15HSD17B10MAPK1 | |
| Hydrochloric Acid SCHEMBL379125 | 0.79 | ALDH1A1 (0.92) | ALDH1A1TSHRALOX15HSD17B10MAPK1 | |
| Hydrochloric Acid SCHEMBL379126 | 0.79 | ALDH1A1 (0.92) | ALDH1A1TSHRALOX15HSD17B10MAPK1 | |
| Hydrochloric Acid SCHEMBL7080476 | 0.76 | ALDH1A1 (0.85) | ALDH1A1TSHRALOX15HSD17B10MAPK1 | |
| SCHEMBL7076748 | 0.76 | ALDH1A1 (0.85) | ALDH1A1TSHRALOX15HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240189360-A1 | COMPOSITIONS AND METHODS TO IMPROVE THE HOMING AND GRAFTING OF HEMATOPOETIC STEM CELLS | 7 HILLS PHARMA INC. (US) | 2024-06-13 | — | — | US | claimed |
| US-20240116939-A1 | CHIRAL OR RACEMIC PYRIMIDINE-FUSED DIAZEPINONE DERIVATIVES, PREPARATION METHOD, AND APPLICATION THEREOF | SUN YAT-SEN UNIVERSITY (CN) | 2024-04-11 | — | — | US | claimed |
| CN-115368363-B | Chiral or racemized pyrimidodiazepinone compound and preparation method and application thereof | 中山大学 | 2024-02-20 | — | — | CN | claimed |
| CN-117164477-A | Synthesis method of 1, n-dinitrile compound | 华南理工大学 | 2023-12-05 | — | — | CN | claimed |
| EP-3838901-B1 | COMPOUND FOR TREATMENT OF RABIES AND METHOD FOR TREATMENT OF RABIES | IRIMAJIRI THERAPEUTICS INC (JP) | 2023-09-27 | — | — | EP | claimed |
| US-11634400-B2 | Micheliolide derivatives, methods for their preparation and their use as anticancer and antiinflammatory agents | UNIVERSITY OF ROCHESTER (US) | 2023-04-25 | — | — | US | claimed |
| CN-114315689-B | Disulfanylphthalimide compound, preparation method and application thereof | 四川大学 | 2023-04-07 | — | — | CN | claimed |
| WO-2023284807-A1 | COMPOUND CONTAINING TETRAHYDRONAPHTHYRIDONE OR TETRAHYDROPYRIDOPYRIMIDINONE SKELETON, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2023-01-19 | — | — | WO | claimed |
| CN-115611896-A | Compound containing tetralone or tetrahydropyridopyrimidone skeleton and preparation method and pharmaceutical application thereof | 中国药科大学 | 2023-01-17 | — | — | CN | claimed |
| CN-115368363-A | Chiral or racemic pyrimido-diazacycloheptanone compound and preparation method and application thereof | 中山大学 | 2022-11-22 | — | — | CN | claimed |
| EP-0125827-A1 | Polyether bisbiguanides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-21 | — | — | EP | claimed |
| EP-0125092-A1 | Bisbiguanide compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-14 | — | — | EP | claimed |
| EP-0125093-A1 | Diaz(ep)ine bis(N-amidinoamidine) derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-14 | — | — | EP | claimed |
| EP-0125091-A2 | 4,4'-Alkylenedipiperidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-14 | — | — | EP | claimed |
| EP-0023097-B1 | DE-ARYLMETHYLATION OF N-MONO- OR N-DIARYLMETHYL-BETA-LACTAMS; NOVEL AZETIZINONES HAVING ANTI-BACTERIAL ACTIVITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-08-01 | — | — | EP | claimed |
| EP-0013608-B1 | SUBSTITUTED BICYCLO (2,2,1)HEPTANES AND HEPT-2-ENES AND THEIR PHARMACEUTICAL COMPOSITIONS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1983-06-15 | — | — | EP | claimed |
| US-4298741-A | DETHIAPENICILLIN ANTIBIOTICS | MERCK & CO., INC. (US) | 1981-11-03 | — | — | US | claimed |
| US-4265891-A | PROSTAGLANDINS, BRONCHODILATORS, PLATELET AGGREGATION INHIBITORS | GLAXO GROUP LIMITED (GB) | 1981-05-05 | — | — | US | claimed |
| EP-0023097-A1 | De-arylmethylation of N-mono- or N-diarylmethyl-beta-lactams; novel azetizinones having anti-bacterial activity | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-01-28 | — | — | EP | claimed |
| US-4232030-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-11-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634400-B2 | Micheliolide derivatives, methods for their preparation and their use as anticancer and antiinflammatory agents | TNF, C9, CYP51A1 | ALDH1A1 1456/4885TSHR 4837/4885ALOX15 5/4885 |
| US-20240116939-A1 | CHIRAL OR RACEMIC PYRIMIDINE-FUSED DIAZEPINONE DERIVATIVES, PREPARATION METHOD, AND APPLICATION THEREOF | GRK1, GRIA1, NR3C1 | ALDH1A1 2293/4885TSHR 2302/4885ALOX15 1732/4885 |
| US-20240189360-A1 | COMPOSITIONS AND METHODS TO IMPROVE THE HOMING AND GRAFTING OF HEMATOPOETIC STEM CELLS | CXCL12, ITGB3, ITGB7 | ALDH1A1 1083/4885TSHR 2351/4885ALOX15 3215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.