Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.40 |
| ▸ | GABRE | P78334 | 2/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846631 | 0.88 | TSHR (0.45) | CLCN2TSHRGABRPGABRDGABRA1 | |
| SCHEMBL10397526 | 0.85 | TSHR (0.47) | CLCN2TSHRGABRPGABRDGABRA1 | |
| SCHEMBL27308477 | 0.84 | CLCN2 (0.54) | CLCN2TSHRGABRPGABRDGABRA1 | |
| SCHEMBL11021926 | 0.83 | CA1 (0.44) | CLCN2TSHRGABRPGABRDGABRA1 | |
| SCHEMBL17509375 | 0.83 | KMT2A (0.38) | CLCN2TSHRALDH1A1KDM4EMEN1 | |
| SCHEMBL9827291 | 0.83 | TSHR (0.41) | CLCN2TSHRGABRPGABRDGABRA1 | |
| Hydrochloric Acid SCHEMBL28243602 | 0.82 | CLCN2 (0.53) | CLCN2TSHRGABRPGABRDGABRA1 | |
| SCHEMBL2498889 | 0.82 | GABRP (0.43) | CLCN2TSHRGABRPGABRDGABRA1 | |
| SCHEMBL28240220 | 0.81 | GABRP (0.45) | CLCN2TSHRGABRPGABRDGABRA1 | |
| SCHEMBL3337887 | 0.81 | ALDH1A1 (0.41) | CLCN2TSHRGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5097068-A | For preparing herbicidal, substituted benzoyl cyclohexanediones | ICI AMERICAS, INC. (US) | 1992-03-17 | — | — | US | disclosed |
| US-4966998-A | FOR PREPARING HERBICIDES, TRISUBSTITUTED BENZOYL CYCLOHEXANEDIONES | ICI AMERICAS INC. (US) | 1990-10-30 | — | — | US | disclosed |
| US-4898973-A | Trisubstituted benzoic acid intermediates | ICI AMERICAS INC. (US) | 1990-02-06 | — | — | US | disclosed |
| EP-0195247-B1 | TRISUBSTITUTED BENZOIC ACID INTERMEDIATES | STAUFFER CHEMICAL COMPANY (US) | 1989-02-08 | — | — | EP | disclosed |
| EP-0195247-A1 | Trisubstituted benzoic acid intermediates | STAUFFER CHEMICAL COMPANY (US) | 1986-09-24 | — | — | EP | disclosed |