Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 6/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 7/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709845 | 1.00 | ACP1 (0.42) | ACP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9709617 | 0.88 | AGTR1 (0.36) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL9709611 | 0.88 | AGTR1 (0.36) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL3058746 | 0.85 | AGTR1 (0.50) | ACP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9710183 | 0.85 | ACP1 (0.41) | ACP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9710180 | 0.85 | ACP1 (0.41) | ACP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9709757 | 0.84 | AGTR1 (0.52) | ACP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9709673 | 0.82 | PDE4A (0.47) | ACP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9709764 | 0.81 | ACP1 (0.40) | ACP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9709710 | 0.81 | PDE4A (0.51) | ACP1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | claimed |
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |