Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | USP1 | O94782 | 2/20 | 0.37 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3058746 | 0.89 | AGTR1 (0.50) | AGTR1AGTR2MEN1KMT2AACP1 | |
| SCHEMBL9709866 | 0.82 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9709759 | 0.82 | AGTR1 (0.45) | AGTR1AGTR2MEN1KMT2AUSP1 | |
| SCHEMBL9709854 | 0.82 | MEN1 (0.63) | AGTR1AGTR2MEN1KMT2AACP1 | |
| SCHEMBL9709642 | 0.81 | AGTR1 (0.48) | AGTR1AGTR2MEN1KMT2A | |
| SCHEMBL9709600 | 0.81 | AGTR1 (0.48) | AGTR1AGTR2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9378493 | 0.81 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9704665 | 0.81 | AGTR1 (0.70) | AGTR1AGTR2 | |
| SCHEMBL9709790 | 0.80 | AGTR1 (0.47) | AGTR1AGTR2MEN1KMT2A | |
| SCHEMBL9709754 | 0.80 | AGTR1 (0.47) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | claimed |
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |