Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COPS5 | Q92905 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 7/20 | 0.33 |
| ▸ | GLS | O94925 | 3/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458127 | 0.91 | HTT (0.40) | COPS5AOC3GLSTLR7 | |
| SCHEMBL9710578 | 0.83 | COPS5 (0.38) | COPS5GLSPTGDR2TLR7 | |
| SCHEMBL9457341 | 0.79 | ALDH1A1 (0.33) | COPS5AOC3TLR7 | |
| SCHEMBL9457502 | 0.78 | PPID (0.42) | ALOX5 | |
| SCHEMBL9710206 | 0.77 | COPS5 (0.36) | COPS5AOC3ALOX5 | |
| SCHEMBL9457473 | 0.77 | ALDH1A1 (0.33) | COPS5AOC3TLR7 | |
| SCHEMBL9457422 | 0.76 | COPS5 (0.44) | COPS5 | |
| SCHEMBL9458088 | 0.74 | CYP3A4 (0.38) | COPS5AOC3 | |
| SCHEMBL9458112 | 0.74 | AOC3 (0.58) | AOC3 | |
| SCHEMBL9710210 | 0.73 | COPS5 (0.37) | COPS5AOC3ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021666-A1 | ANGIOTENSIN II RECEPTOR ANTAGONIST THIAZOLE DEVIVATIVES | LABORATOIRES UPSA (FR) | 1992-12-10 | — | — | WO | disclosed |