Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COPS5 | Q92905 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | PPID | Q08752 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
| ▸ | PPIB | P23284 | 1/20 | 0.34 |
| ▸ | PPIA | P62937 | 1/20 | 0.34 |
| ▸ | PPIG | Q13427 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710190 | 0.86 | RAB9A (0.41) | LMNAMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9457502 | 0.76 | PPID (0.42) | HSP90AA1LMNACYP1A2CYP3A4MAOA | |
| SCHEMBL9458088 | 0.75 | CYP3A4 (0.38) | COPS5CYP1A2CYP3A4ALDH1A1NPC1 | |
| SCHEMBL9458014 | 0.75 | MAPT (0.42) | PPIDALDH1A1MAPTHPGDSHMT2 | |
| SCHEMBL9457422 | 0.74 | COPS5 (0.44) | COPS5CYP1A2CYP3A4ALDH1A1MAPT | |
| SCHEMBL9710207 | 0.73 | COPS5 (0.36) | COPS5ALOX5AOC3 | |
| SCHEMBL9710206 | 0.73 | COPS5 (0.36) | COPS5HSP90AA1ALOX5XIAPAOC3 | |
| SCHEMBL9458127 | 0.73 | HTT (0.40) | COPS5ALDH1A1GAAHSD17B10HTT | |
| SCHEMBL9458112 | 0.72 | AOC3 (0.58) | XIAPTSHRAOC3 | |
| SCHEMBL9458070 | 0.70 | AOC3 (0.45) | COPS5XIAPAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021666-A1 | ANGIOTENSIN II RECEPTOR ANTAGONIST THIAZOLE DEVIVATIVES | LABORATOIRES UPSA (FR) | 1992-12-10 | — | — | WO | disclosed |