Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 2/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27308477 | 0.82 | CLCN2 (0.54) | CLCN2METAP2KMT2AALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL28243602 | 0.80 | CLCN2 (0.53) | CLCN2METAP2KMT2AALDH1A1MEN1 | |
| SCHEMBL8467585 | 0.80 | CLCN2 (0.42) | CLCN2METAP2CTRCKMT2AGAA | |
| SCHEMBL9710259 | 0.78 | CLCN2 (0.43) | CLCN2METAP2CTRCKMT2AGAA | |
| SCHEMBL12658946 | 0.78 | CTRC (0.48) | CLCN2METAP2CTRCGABRA1GABRB2 | |
| SCHEMBL11877622 | 0.76 | CLCN2 (0.39) | CLCN2METAP2CTRCKMT2AGAA | |
| SCHEMBL19987931 | 0.71 | CNR2 (0.40) | CLCN2GAAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28750906 | 0.71 | CLCN2 (0.48) | CLCN2METAP2KMT2AALDH1A1MEN1 | |
| SCHEMBL11138516 | 0.71 | CLCN2 (0.48) | CLCN2METAP2KMT2AALDH1A1MEN1 | |
| SCHEMBL15796239 | 0.71 | HSD17B1 (0.35) | HSD17B1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5097068-A | For preparing herbicidal, substituted benzoyl cyclohexanediones | ICI AMERICAS, INC. (US) | 1992-03-17 | — | — | US | disclosed |
| US-4966998-A | FOR PREPARING HERBICIDES, TRISUBSTITUTED BENZOYL CYCLOHEXANEDIONES | ICI AMERICAS INC. (US) | 1990-10-30 | — | — | US | disclosed |
| US-4898973-A | Trisubstituted benzoic acid intermediates | ICI AMERICAS INC. (US) | 1990-02-06 | — | — | US | disclosed |
| EP-0195247-A1 | Trisubstituted benzoic acid intermediates | STAUFFER CHEMICAL COMPANY (US) | 1986-09-24 | — | — | EP | disclosed |