Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | CAD | P27708 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338079 | 0.83 | ALOX15 (0.52) | ALOX15ALDH1A1HPGDCADHSD17B10 | |
| Hydrochloric Acid SCHEMBL275716 | 0.80 | ALOX15 (0.50) | ALOX15ALDH1A1HPGDCADHSD17B10 | |
| SCHEMBL2372063 | 0.77 | ALOX15 (0.48) | ALOX15ALDH1A1HPGDAURKANTRK1 | |
| SCHEMBL2117569 | 0.77 | ALDH1A1 (0.56) | ALOX15ALDH1A1HPGDAURKANTRK1 | |
| SCHEMBL15083214 | 0.76 | ALOX15 (0.46) | ALOX15ALDH1A1CADHSD17B10LMNA | |
| SCHEMBL4405650 | 0.76 | ALOX15 (0.46) | ALOX15ALDH1A1CADHSD17B10LMNA | |
| SCHEMBL1340978 | 0.76 | ALDH1A1 (0.48) | ALOX15ALDH1A1HPGDCADHSD17B10 | |
| Acetic Acid SCHEMBL28002636 | 0.76 | ALDH1A1 (0.48) | ALOX15ALDH1A1HPGDCADHSD17B10 | |
| SCHEMBL12582818 | 0.76 | ALOX15 (0.46) | ALOX15ALDH1A1CADHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL11068821 | 0.76 | ALOX15 (0.46) | ALOX15ALDH1A1HPGDAURKANTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021666-A1 | ANGIOTENSIN II RECEPTOR ANTAGONIST THIAZOLE DEVIVATIVES | LABORATOIRES UPSA (FR) | 1992-12-10 | — | — | WO | disclosed |