Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL9710300 | 0.85 | MAPT (0.43) | POLBKCNH2MEN1KMT2AMAPT | |
| SCHEMBL9710287 | 0.80 | POLB (0.46) | POLBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9457601 | 0.76 | KCNH2 (0.47) | POLBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9457581 | 0.74 | KCNH2 (0.45) | POLBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4737258 | 0.74 | KCNH2 (0.67) | KCNH2MAPTALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL18045530 | 0.72 | KCNH2 (0.65) | KCNH2MAPTALDH1A1RAB9ATSHR | |
| SCHEMBL9457404 | 0.71 | MEN1 (0.44) | POLBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9710262 | 0.71 | TSHR (0.39) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL9457465 | 0.69 | POLB (0.42) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL680595 | 0.69 | KCNH2 (0.74) | KCNH2MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021666-A1 | ANGIOTENSIN II RECEPTOR ANTAGONIST THIAZOLE DEVIVATIVES | LABORATOIRES UPSA (FR) | 1992-12-10 | — | — | WO | disclosed |