Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710327 | 0.91 | MAPT (0.37) | TSHRTDP1CYP3A4ALDH1A1MAPT | |
| Propionic Acid SCHEMBL9710382 | 0.91 | COPS5 (0.36) | TSHRTDP1CYP3A4ALDH1A1MAPT | |
| SCHEMBL22701211 | 0.76 | CYP1A2 (0.36) | TDP1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9457422 | 0.75 | COPS5 (0.44) | TSHRTDP1CYP3A4ALDH1A1MAPT | |
| SCHEMBL9458088 | 0.74 | CYP3A4 (0.38) | TSHRTDP1CYP3A4ALDH1A1GFER | |
| SCHEMBL16502343 | 0.74 | KDM4E (0.39) | ALDH1A1MEN1KMT2ALMNA | |
| Propionic Acid SCHEMBL9710300 | 0.73 | MAPT (0.43) | TSHRALDH1A1MAPTMEN1RAB9A | |
| SCHEMBL12866934 | 0.71 | KDM4E (0.35) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9710242 | 0.71 | ENPP1 (0.36) | TSHRTDP1CYP3A4ALDH1A1MAPT | |
| SCHEMBL12881961 | 0.70 | KDM4E (0.32) | ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021666-A1 | ANGIOTENSIN II RECEPTOR ANTAGONIST THIAZOLE DEVIVATIVES | LABORATOIRES UPSA (FR) | 1992-12-10 | — | — | WO | disclosed |